Abstract
Cardiovascular heart disease is one of the leading health issues in the present era and requires considerable health care resources to prevent it. The present study was focused on the development of a new coronary stent based on novel auxetic geometry which enables the stent to exhibit a negative Poisson’s ratio. Commercially available coronary stents have isotropic properties, whereas the vascular system of the body shows anisotropic characteristics. This results in a mismatch between anisotropic–isotropic properties of the stent and arterial wall, and this in turn is not favorable for mechanical adhesion of the commercially available coronary stents with the arterial wall. It is believed that an auxetic coronary stent with inherent anisotropic mechanical properties and negative Poisson’s ratio will have good mechanical adhesion with the arterial wall.
The auxetic design was obtained via laser cutting, and surface treatment was performed with acid pickling and electropolishing, followed by an annealing process. In vitro mechanical analysis was performed to analyze the mechanical performance of the auxetic coronary stent. Scanning electronic microscopy (SEM) was used to determine the effects of fabrication processes on the topography of the auxetic stent.
The elastic recoil (3.3%) of the in vitro mechanical analysis showed that the auxetic stent design effectively maintained the luminal patency of the coronary artery. Also, the auxetic coronary stent showed no foreshortening, therefore it avoids the problem of stent migration, by expanding in both the radial and longitudinal directions. By virtue of its synclastic behavior, the auxetic stent bulges outward when it is radially expanded through an inflated balloon.
J Appl Biomater Funct Mater 2015; 13(2): e127 - e135
Article Type: ORIGINAL RESEARCH ARTICLE
DOI:10.5301/jabfm.5000213
Authors
Faisal Amin, Murtaza Najabat Ali, Umar Ansari, Mariam Mir, Muhammad Asim Minhas, Wakeel ShahidArticle History
- • Accepted on 15/05/2014
- • Available online on 30/10/2014
- • Published online on 04/07/2015
Disclosures
This article is available as full text PDF.
Authors
- Amin, Faisal [PubMed] [Google Scholar] 1
- Ali, Murtaza Najabat [PubMed] [Google Scholar] 1, * Corresponding Author ([email protected])
- Ansari, Umar [PubMed] [Google Scholar] 1
- Mir, Mariam [PubMed] [Google Scholar] 1
- Minhas, Muhammad Asim [PubMed] [Google Scholar] 2
- Shahid, Wakeel [PubMed] [Google Scholar] 2
Affiliations
-
Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), Islamabad - Pakistan -
Experimental Physics Facility, National Center for Physics, Islamabad - Pakistan
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