Advertisement

Characterization of oligo(ethylene glycol) and oligoglycerol functionalized poly(ether imide) by angle-dependent X-ray photoelectron spectroscopy

Abstract

Purpose: Previous investigations have shown that poly(ether imide) (PEI) membranes can be functionalized with aminated macromolecules. In this study we explored whether the characterization of PEI functionalized with oligo(ethylene glycol) (OEG) or linear, side chain methylated oligoglycerols (OGMe), by angle-dependent X-ray induced photoelectron spectroscopy (XPS) can be used to prove the functionalization, give insight into the reaction mechanism and reveal the spatial distribution of the grafts. 
Methods: PEI membranes were functionalized under alkaline conditions using an aqueous solution with 2 wt% of α-amino-ω-methoxy oligo(ethylene glycol) (Mn = 1,320 g·mol-1) or linear, side chain methylated monoamine oligoglycerols (Mn = 1,120, 1,800 or 2,270 g·mol-1), respectively. The functionalized membranes were investigated using XPS measurements at different detector angles to enable comparison between the signals related to the bulk and surface volume and were compared with untreated and alkaline-treated PEI membranes.
 Results: While at a perpendicular detector angle the bulk signals of the PEI were prominent, at larger surface volume-related detector angles, the signals for OGMe and OEG were determinable. 
Conclusion: The surface functionalization of PEI with OEG and OGMe could be verified by the angle-dependent XPS. The observations proved the functionalization at the PEI surface, as the polyethers were detected at angles providing signals of the surface volume. Furthermore, the chemical functions determined verified a covalent binding via the nucleophilic addition of the amine functionalized OGMe and OEG to the PEI imide function.

J Appl Biomater Funct Mater 2012; 10(3): 215 - 222

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/JABFM.2012.10345

Authors

Maik von Ruesten-Lange, Karola Luetzow, Axel T. Neffe, Andreas Lendlein

Article History

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

  • von Ruesten-Lange, Maik [PubMed] [Google Scholar]
    Center for Biomaterial Development and Berlin-Brandenburg Centre for Regenerative Therapies, Institute of Polymer Research, Helmholtz-Zentrum Geesthacht - Germany and Institute of Chemistry, University of Potsdam, Potsdam - Germany
  • Luetzow, Karola [PubMed] [Google Scholar]
    Center for Biomaterial Development and Berlin-Brandenburg Centre for Regenerative Therapies, Institute of Polymer Research, Helmholtz-Zentrum Geesthacht - Germany
  • Neffe, Axel T. [PubMed] [Google Scholar]
    Center for Biomaterial Development and Berlin-Brandenburg Centre for Regenerative Therapies, Institute of Polymer Research, Helmholtz-Zentrum Geesthacht - Germany and Institute of Chemistry, University of Potsdam, Potsdam - Germany
  • Lendlein, Andreas [PubMed] [Google Scholar]

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.