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< Vol. 11 Issue 1 | Jan-Apr 2013 | pp. 1 - 71

Characterization of the mechanical and biological properties of a new alumina scaffold

Abstract

Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. Conclusions: The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.

J Appl Biomater Funct Mater 2013; 11(1): 18 - 25

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/JABFM.2012.9264

Authors

Patrícia SP. Batista, Miguel AA. Rodrigues, Daniela MR. Silva, Patrícia IC. Morgado, Joaquim P. Henriques, Maria O. Almeida, Abílio P. Silva, Ilídio J. Correia

Article History

  • • Accepted on 09/03/2012
  • • Available online on 22/06/2012
  • • Published online on 24/06/2013

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Authors

  • Batista, Patrícia SP. [PubMed] [Google Scholar]
    CICS-UBI - Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã - Portugal
  • Rodrigues, Miguel AA. [PubMed] [Google Scholar]
    CICS-UBI - Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã - Portugal
  • Silva, Daniela MR. [PubMed] [Google Scholar]
    CICS-UBI - Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã - Portugal
  • Morgado, Patrícia IC. [PubMed] [Google Scholar]
    CICS-UBI - Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã - Portugal
  • Henriques, Joaquim P. [PubMed] [Google Scholar]
    CICS-UBI - Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã - Portugal
  • Almeida, Maria O. [PubMed] [Google Scholar]
    Egas Moniz, Higher Education Cooperative, Monte de Caparica - Portugal
  • Silva, Abílio P. [PubMed] [Google Scholar]
    CAST - Centre for Aerospace Science and Technologies, University of Beira Interior, Covilhã - Portugal
  • Correia, Ilídio J. [PubMed] [Google Scholar]
    CICS-UBI - Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior, Covilhã - Portugal

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