Advertisement

Influence of pastes containing casein phosphopeptide-amorphous calcium phosphate on surface of demineralized enamel

Abstract

Purpose

The purpose of the study was to evaluate the surface characteristics of demineralized enamel after treatment with pastes containing casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) or casein phosphopeptide–amorphous calcium fluoride phosphate (CPP-ACFP) and to compare their efficacy with that of 0.05% NaF.

Methods

Following formation of the artificial carious lesion, enamel slabs were divided into 4 groups (CPP-ACP, CPP-ACFP, 0.05% NaF and control) and submitted to a chemical caries model. Remineralization potential was examined using scanning electron microscope, energy-dispersive spectroscopy (EDS) and microhardness test. Scanning electron microphotographs were analyzed for area, minimal, maximal and mean diameter, perimeter, roundness and number of enamel defects and percentage of tooth surface affected by defects.

Results

Treatment with 0.05% NaF partly reduced the appearance of enamel defects when compared with irregular demineralized enamel. Treatment with CPP-ACP or CPP-ACFP resulted in occlusion of defects which produced more flattened enamel surface. Image analysis revealed reduction of the dimensions of the defects in the 3 experimental groups. Treatment with CPP-ACFP decreased the number of enamel defects when compared with demineralized enamel. The EDS analysis did not show differences in Ca/O, P/O and Ca/P ratios between the groups (P>0.05). Microhardness test revealed significant effects of CPP-ACP and CPP-ACFP (P<0.05).

Conclusions

Pastes containing CPP-ACP or CPP-ACFP showed potential to remineralize enamel surface lesions.

J Appl Biomater Funct Mater 2014; 12(3): 234 - 239

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/jabfm.5000194

Authors

Tamara O. Peric, Dejan L.J. Markovic, Vesna J. Radojevic, Radmila M. Jancic Heinemann, Bojan B. Petrovic, Jelena S. Lamovec

Article History

Disclosures

Financial support: This research is a result of Project No. 172026 supported by the Ministry of Education and Science of Serbia.
Conflict of interest: The authors declare that they have no competing interests. GC Int. (Tokyo, Japan) and Curaden International AG (Kriens, Switzerland) provided the materials, but no funding for this study. The authors do not hold any stocks or shares in an organization that may in any way gain or lose financially from the publication of this manuscript.

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

Affiliations

  • Department of Pediatric and Preventive Dentistry, Faculty of Dentistry, University of Belgrade, Belgrade - Serbia
  • Department of Materials Science and Engineering, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade - Serbia
  • Department of Pediatric and Preventive Dentistry, Dentistry Clinic of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad - Serbia
  • Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade - Serbia

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.