Abstract
Natural polymers, because of their biocompatibility, availability, and physico-chemical properties have been the materials of choice for the fabrication of injectable hydrogels for regenerative medicine. In particular, they are appealing materials for delivery systems and provide sustained and controlled release of drugs, proteins, gene, cells, and other active biomolecules immobilized.In this work, the use of hydrogels obtained from natural source polymers as cell delivery systems is discussed. These materials were investigated for the repair of cartilage, bone, adipose tissue, intervertebral disc, neural, and cardiac tissue. Papers from the last ten years were considered, with a particular focus on the advances of the last five years. A critical discussion is centered on new perspectives and challenges in the regeneration of specific tissues, with the aim of highlighting the limits of current systems and possible future advancements.
J Appl Biomater Funct Mater 2012; 10(2): 67 - 81
Article Type: REVIEW
DOI:10.5301/JABFM.2012.9418
Authors
Fabiola Munarin, Paola Petrini, Sabrina Bozzini, Maria Cristina Tanzi
Article History
- • Accepted on 04/07/2012
- • Available online on 02/08/2012
- • Published online on 27/09/2012
This article is available as full text PDF.
Authors
- Munarin, Fabiola
[PubMed]
[Google Scholar]
Laboratorio di Biomateriali, Bioengineering Department and UdR INSTM Milano Politecnico, Politecnico di Milano, Milan - Italy
- Petrini, Paola
[PubMed]
[Google Scholar]
Laboratorio di Biomateriali, Bioengineering Department and UdR INSTM Milano Politecnico, Politecnico di Milano, Milan - Italy
- Bozzini, Sabrina
[PubMed]
[Google Scholar]
Laboratorio di Biomateriali, Bioengineering Department and UdR INSTM Milano Politecnico, Politecnico di Milano, Milan - Italy
- Tanzi, Maria Cristina
[PubMed]
[Google Scholar]
Laboratorio di Biomateriali, Bioengineering Department and UdR INSTM Milano Politecnico, Politecnico di Milano, Milan - Italy
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