Prevention of Staphylococcus epidermidis biofilm formation using electrical current

Del Pozo, Jose L.; Rouse, Mark S.; Euba, Gorane; Greenwood-Quaintance, Kerryl E.; Mandrekar, Jayawant N.; Steckelberg, James M.; Patel, Robin

doi:10.5301/jabfm.5000208

Prevention of Staphylococcus epidermidis biofilm formation using electrical current

Abstract

A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 10³ cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log₁₀ cfu/cm² were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log₁₀ cfu/cm² were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log₁₀ cfu/cm² were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.

J Appl Biomater Funct Mater 2014; 12(2): 81 - 83

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/jabfm.5000208

Authors

Jose L. Del Pozo, Mark S. Rouse, Gorane Euba, Kerryl E. Greenwood-Quaintance, Jayawant N. Mandrekar, James M. Steckelberg, Robin Patel

Article History

• Accepted on 30/11/2013
• Available online on 25/07/2014
• Published online on 05/09/2014

Disclosures

Financial support: The project described was supported by R01 AI0191594 and R21 AI061407 from NIAID/NIH, and ROI AR056647 from NIAMS/NIH.

Conflict of interest: None

This article is available as full text PDF.

If you are a Subscriber, please log in now.
Article price: Eur 36,00
You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
Article added to cart
If you are not a Subscriber you may:
Subscribe to this journal
Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

Del Pozo, Jose L. [PubMed] [Google Scholar] 1, 2
Rouse, Mark S. [PubMed] [Google Scholar] 2
Euba, Gorane [PubMed] [Google Scholar] 1, 2
Greenwood-Quaintance, Kerryl E. [PubMed] [Google Scholar] 2, 4
Mandrekar, Jayawant N. [PubMed] [Google Scholar] 3
Steckelberg, James M. [PubMed] [Google Scholar] 1, 2
Patel, Robin [PubMed] [Google Scholar] 1, 2, 4, * Corresponding Author ([email protected])

Affiliations

1 Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota - USA
2 Infectious Diseases Research Laboratory, Mayo Clinic College of Medicine, Rochester, Minnesota - USA
3 Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota - USA
4 Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota - USA

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.