Abstract
Purpose: The purpose of this study was to assess a new metal component finishing designed to improve total knee prosthesis durability. Wear of ultrahigh molecular-weight polyethylene (UHMWPE), with generation of submicrometer- and micrometer-sized particles, has been associated with osteolysis and artificial joint failure. Wear extent is influenced by several factors, some of which are related to manufacturing. Methods: UHMWPE wear was assessed in metal prosthesis components finished with the Microloy® technology and in traditionally finished components by wear simulation experiments (pin on disk and knee simulator tests) and analysis of wear debris. Results: Microloy®-finished prosthesis showed a 48.5% reduction in UHMWPE total weight loss compared with traditional components (P=0.002). A statistically significant (P>0.05) reduction of UHMWPE debris were detected from the Microloy®-finished compared with the traditionally finished components. Conclusions: These findings suggest the Microloy® metal finishing may enhance the long-term performance of knee prostheses.
J Appl Biomater Funct Mater 2013; 11(2): 99 - 105
Article Type: ORIGINAL RESEARCH ARTICLE
DOI:10.5301/JABFM.5000153
Authors
Antonio Gigante, Valerio Cigna, Sandra Manzotti, Tommaso Villa, Eleonora Salvolini, Monica Mattioli-Belmonte
Article History
- • Accepted on 22/10/2012
- • Available online on 31/05/2013
- • Published online on 13/09/2013
This article is available as full text PDF.
Authors
- Gigante, Antonio
[PubMed]
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Department of Clinical and Molecular Sciences, School of Medicine, Università Politecnica delle Marche, Ancona - Italy
- Cigna, Valerio
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Department of Clinical and Molecular Sciences, School of Medicine, Università Politecnica delle Marche, Ancona - Italy
- Manzotti, Sandra
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Department of Clinical and Molecular Sciences, School of Medicine, Università Politecnica delle Marche, Ancona - Italy
- Villa, Tommaso
[PubMed]
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Department of Structural Engineering, Milan Polytechnic and IRCCS Galeazzi Orthopedic Institute, Milano - Italy
- Salvolini, Eleonora
[PubMed]
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Department of Clinical and Molecular Sciences, School of Medicine, Università Politecnica delle Marche, Ancona - Italy
- Mattioli-Belmonte, Monica
[PubMed]
[Google Scholar]
Department of Clinical and Molecular Sciences, School of Medicine, Università Politecnica delle Marche, Ancona - Italy
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